At ambient temperature, the degradation half-life is approximately 2.8 hours at pH 5 and approximately 220 hours at pH 7.8. The rate of degradation increases with decreasing pH. The stability of the compound in aqueous solution is pH-dependent. Pantoprazole sodium sesquihydrate is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium sesquihydrate is a white to off-white crystalline powder and is racemic. Its empirical formula is C 16H 14F 2N 3NaO 4S x 1.5 H 2O, with a molecular weight of 432.4. The active ingredient in PROTONIX (pantoprazole sodium) For Delayed-Release Oral Suspension and PROTONIX (pantoprazole sodium) Delayed-Release Tablets, a PPI, is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2- sulfinyl]-1 H-benzimidazole sesquihydrate, a compound that inhibits gastric acid secretion. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. These are not all the possible side effects of Prometrium. Tell your doctor if you have any side effect that bothers you or that does not go away. cold symptoms (most common in children).The most common side effects of Protonix include: Get medical help right away, if you have any of the symptoms listed above. skin rash on your cheeks or arms which worsens at night.muscle cramps or spasms in your hands or feet,.bruising or swelling at the injection site,.sudden pain or difficulty moving your hip, wrist or back,.diarrhea that is watery or has blood in it,.Protonix may cause serious side effects, including: What are the possible side effects of Protonix? It is not known if Protonix is safe and effective in children younger than 5 years of age. Protonix belongs to a class of drugs called proton pump inhibitors (PPIs). Protonix may be used alone or with other medications. Protonix is a prescription medicine used to treat the symptoms of esophagitis caused by stomach acid due to gastroesophageal reflux disease or GERD and Zollinger-Ellison syndrome or other conditions causing excess stomach acid.
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